SEICAP MADRID 2014 - page 136

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Inmunoterapia oral y alergia a alimentos (OIT): Pros- CONS
7.
Skripak, J.; Matsui, E.; Mudd, K.;
Wood, R. The natural history of
IgE-mediated cow’s milk allergy. J.
Allergy Clin. Immunol. 2007, 120,
1172–1177.
8.
Scurlock AM, Burks AW, Jones SM.
Oral immunotherapy for food aller-
gy.
Curr Allergy Asthma Rep
2009; 9:
186-93.
9.
Chase MW. Inhibition of experimen-
tal drugallergy by prior feeding of
the sensitizing agent. Proc Soc Exp
BiolMed 1946: 61: 257–9.
10.
Chehade M, Mayer L. Oral tolerance
and its relation to food hypersensiti-
vities. J Allergy Clin Immunol 2005:
115: 3–12;
11.
Giuseppe Crisafulli PhD, Lucia Ca-
miniti MD and Giovanni B. Pajno
MD. Oral Desensitization for Im-
munoglobulin E-Mediated Milk and
Egg Allergies : IMAJ 2012; 14: 53–56
12.
Buchanan AD, GreenTD, Jones SM,
Scurlock AM, Christie L, Althage KA,
Steele PH, Pons L, Helm RM, Lee LA,
Burks AW. Egg oral immunotherapy
in nonanaphylactic children with
egg allergy. J Allergy Clin Immunol.
2007 ;119(1):199-205.
13.
Milk oral immunotherapy is effecti-
ve in school-aged children.Salmive-
si S, Korppi M, Mäkelä MJ, Paassilta
M.Acta Paediatr. 2013;102(2):172-6
14 BurksAW, Jones SM,Wood RA, Fleis-
cher DM, Sicherer SH, Lindblad RW,
Stablein D, Henning AK, Vickery BP,
Liu AH, Scurlock AM, Shreffler WG,
Plaut M, Sampson HA; Consortium
of Food Allergy Research (CoFAR).
Oral immunotherapy for treatment
of egg allergy in children N Engl J
Med. 2012 Jul 19;367(3):233-43
15 Narisety S, Skripak J, Wood RA.
Long-term follow-up of oral im-
munotherapy for cow’s milk aller-
gy J Allergy Clin Immunol. 2013
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16.
Keet, C.A.; Frischmeyer-Guerrerio,
P.A.; Thyagarajan, A.; Schroeder,
J.T.; Hamilton, R.G.; Boden, S.; Ste-
Mientras buscamos las respuestas debe-
ríamos tratar de uniformizar objetivos:
– Homogeneizar las diferentes pautas y
criterios de selección
– Minimizar las reacciones adversas
– Buscar un marcador que discrimine a los
respondedores
– Hacer más factible el seguimiento
En esta espera, para concluir tomo pres-
tadas las palabras de la una muy reciente
revisión crítica con meta análisis “La Inmu-
noterapia oral no se acomoda a la práctica
clínica rutinaria y no debe ser considerada,
bajo ninguna circunstancia, un tratamiento
que pueda ser auto administrado”.
(33)
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