187
Omalizumab reduced asthma
exacerbations*
*Requiring doubling of the inhaled corticosteroid dose or addition of
oral corticosteroids during the steroid reduction phase.
RRR = relative rate reduction.
Milgrom H,
et al. Pediatrics
2001;108:e36.
0,42
0,72
0,0
0,1
0,2
0,3
0,4
0,5
0,6
0,7
0,8
Exacerbation rate
(mean number of episodes per patient)
Omalizumab
(n=216)
Placebo
(n=101)
p<0.001
010
RRR
42%
ICS dose reduced in children
receiving omalizumab
ICS = inhaled corticosteroids.
Milgrom H,
et al. Pediatrics
2001;108:e36.
Median reduction
in ICS dose
Omalizumab
n=216
Placebo
n=101
100%
≥75% reduction
in ICS dose
100% reduction
in ICS dose
010
65%
55%
66.7%
49%
39%
Simposium
