127
Simposium
creased after purification (depigmen-
tation) step. Allergy 2011; 66(Suppl.
94): 291 (abstract-poster).
8. Iraola V, Gallego MT, López-Matas MA,
Morales M, Bel I, García N, Carnés J.
Immunogenicity of Phleum pratense
Depigmented AllergoidVaccines: Experi-
mental Study in Rabbits. J Investig Aller-
gol Clin Immunol 2012;Vol 22(1): 35-40.
9. Norman PS, Lichtenstein LM, Marsh
DG. Studies on allergoids from natura-
lly occuring allergens. IV. Effi cacy and
safety of longterm allergoid treatment
of ragweed hay fever. J Allergy Clin
Immunol. 1981;68:460-70.
10. Van Metre TE et al. A comparison of
immunotherapy schedules for in-
jection treatment of ragweed pollen
hay fever. J.Allergy Clin. Immunol.
1982;69:181-93.
11. Ameal A, Vega-Chicote JM, Fernán-
dez S, Miranda A, Carmona MJ, Ron-
dón MC, Reina E, García-González JJ.
Double-Blind and Placebo-Controlled
study to assess efficacy and safety of
a modified allergen extract of
Derma-
tophagoides pteronyssinus
in allergic
asthma. Allergy 2005; 60: 1178-1183.
12. García-Robaina JC, Sánchez I, de laTo-
rre F, Fernández-Caldas E, Casanovas
M. Successful treatment of mite aller-
gic asthma with modified extracts of
D. pteronyssinus
and
D. farinae
in a
double-blind placebo-controlled stu-
dy. J Allergy Clin Immunol 2006; 118:
1026-1032.
Bibliografía:
1. Alergológica 2005.
2. Iraola V. et al. Mapa acarológico de Es-
paña 2009.
3. Des Roches A, Paradis L, Menardo
JL, Bouges S, Daures JP, Bousquet J.
Immunotherapy with a standardized
Dermatophagoides pteronyssinus ex-
tract. VI. Specific immunotherapy pre-
vents the onset of new sensitizations
in children. J Allergy Clin Immunol
1997;99:450-453.
4. Durham SR, Walker SM, VArga EM,
Jacobson MR, O´Brien F, Noblew, Till
SJ, Hamidqa, Nouri-Aria KT. Long-
term clinical efficacy of grass-po-
llen immunotherapy. N Engl J Med.
1999;341:468-75
5. Van Metre TE et al. A comparison of
immunotherapy schedules for in-
jection treatment of ragweed pollen
hay fever. J.Allergy Clin. Immunol.
1982;69:181-93.
6. Carnés J, Gallego MT, Casanovas M,
Ferrer A, Fernández-Caldas E. Cha-
racterisation of low molecular weight
components released during the de-
pigmentation process of
Betula ve-
rrucosa
(
alba
) and
Dermatophagoides
pteronyssinus
. XXII EAACI Congress,
Amsterdam 2004).
7.
Iraola V, Gallego MT, Morales M, Le-
onor JR, Carnés J. Immunogenicity of
birch pollen extract is significantly in-




